Ah, I remember the a bit older times when you had to check the compatibility of your pieces as a graphic card a bit better than your CPU or motherboard would kill your PC.Since graph cars have their own CPU that's no longer a problem, as Gunny said.
That's what I meant with killing your PC, "your CPU won't be able to load it properly" and that can be seen in different ways. When it goes really slow, it's like dead... no one wants a slower PC than they had before.